Neuroprotective mechanism of salvianolic acid B against cerebral ischemia–reperfusion injury in mice through downregulation of TLR4, p‐p38MAPK, p‐JNK, NF‐κB, and IL‐1β

Abstract Objective Tissue injury and inflammation are two potential outcomes of cerebral ischemia–reperfusion (I/R) injury. Salvianolic acid B (Sal B), isolated from the roots of Salvia miltiorrhiza, is one of the major water‐soluble compounds with a wide range of pharmacological effects including a...

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Bibliographic Details
Main Authors: Xiu‐fen Zheng, Xiang‐jian Zhang, Li‐peng Dong, Jing‐ru Zhao, Cong Zhang, Rong Chen
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.1030