Antibody drug conjugates targeting HER2: Clinical development in metastatic breast cancer

The identification of the HER2 alteration as an actionable oncogenic driver in breast cancer has propelled the development of HER-targeting monoclonal antibodies (mAb) such as trastuzumab and pertuzumab, which led to dramatic improvements in survival outcomes. Lately, the great strides made toward d...

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Bibliographic Details
Main Authors: Elie Rassy, Layal Rached, Barbara Pistilli
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Breast
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977622001813