Disruption of a putative mitochondrial oxaloacetate shuttle protein in Aspergillus carbonarius results in secretion of malic acid at the expense of citric acid production

Disruption of a putative mitochondrial oxaloacetate shuttle protein in Aspergillus carbonarius results in secretion of malic acid at the expense of citric acid production

Abstract Background In filamentous fungi, transport of organic acids across the mitochondrial membrane is facilitated by active transport via shuttle proteins. These transporters may transfer different organic acids across the membrane while taking others the opposite direction. In Aspergillus niger...

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Bibliographic Details
Main Authors: Lei Yang, Tore Linde, Abeer H. Hossain, Mette Lübeck, Peter J. Punt, Peter S. Lübeck
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Biotechnology
Subjects:
Aspergillus carbonarius
Mitochondrial transport protein
Citric acid
Malic acid
Metabolic engineering
Online Access:http://link.springer.com/article/10.1186/s12896-019-0572-0

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http://link.springer.com/article/10.1186/s12896-019-0572-0

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