Listeriolysin O is necessary and sufficient to induce autophagy during Listeria monocytogenes infection.

Recent studies have suggested that autophagy is utilized by cells as a protective mechanism against Listeria monocytogenes infection.However we find autophagy has no measurable role in vacuolar escape and intracellular growth in primary cultured bone marrow derived macrophages (BMDMs) deficient for...

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Bibliographic Details
Main Authors: Nicole Meyer-Morse, Jennifer R Robbins, Chris S Rae, Sofia N Mochegova, Michele S Swanson, Zijiang Zhao, Herbert W Virgin, Daniel Portnoy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2797616?pdf=render