Sex-specific effect of P2Y2 purinergic receptor on glucose metabolism during acute inflammation

Sex-specific effect of P2Y2 purinergic receptor on glucose metabolism during acute inflammation

The sex of an animal impacts glucose sensitivity, but little information is available regarding the mechanisms causing that difference, especially during acute inflammation. We examined sex-specific differences in the role of the P2Y2 receptor (P2Y2R) in glucose flux with and without LPS challenge....

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Bibliographic Details
Main Authors: Randi J. Ulbricht, Christian A. Rivas, Hailee Marino, Erin Snyder, Dana James, Jamila Makhloufi, Nathan Johnson, Scott Zimmerman, Jianjie Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Endocrinology
Subjects:
purinergic signaling
glucose homeostasis
P2Y receptor
inflammation
sex-dependence
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1248139/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1248139/full

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