Expression of ABCA1 Transporter and LXRA/LXRB Receptors in Placenta of Women with Late Onset Preeclampsia

Expression of ABCA1 Transporter and LXRA/LXRB Receptors in Placenta of Women with Late Onset Preeclampsia

Background: Appropriate levels of cholesterol are necessary for the mother and developing fetus, but theirexcess may cause preeclampsia. The ABCA1 transporter mediates the secretion of cholesterol and is highly regulated at the transcriptional level via the nuclear liver X receptors (LXRs). Methods:...

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Bibliographic Details
Main Authors: Hubert Wolski, Marcin Ożarowski, Grażyna Kurzawińska, Anna Bogacz, Marlena Wolek, Małgorzata Łuszczyńska, Krzysztof Drews, Aleksandra E. Mrozikiewicz, Przemysław Ł. Mikołajczak, Radosław Kujawski, Bogusław Czerny, Tomasz M. Karpiński, Agnieszka Seremak-Mrozikiewicz
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Journal of Clinical Medicine
Subjects:
preeclampsia (PE)
adenosine triphosphate-binding cassette transporter A1 (ABCA1)
liver X receptors (LXRs)
gene expression
protein level
Online Access:https://www.mdpi.com/2077-0383/11/16/4809

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https://www.mdpi.com/2077-0383/11/16/4809

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