Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization.

Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization.

The development of a universal vaccine against foot-and-mouth disease virus (FMDV) is hindered by cross-serotype antigenic diversity and by a lack of knowledge regarding neutralization of the virus in natural hosts. In this study, we isolated serotype O-specific neutralizing antibodies (NAbs) (F145...

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Bibliographic Details
Main Authors: Yong He, Kun Li, Yimei Cao, Zixian Sun, Pinghua Li, Huifang Bao, Sheng Wang, Guoqiang Zhu, Xingwen Bai, Pu Sun, Xuerong Liu, Cheng Yang, Zaixin Liu, Zengjun Lu, Zihe Rao, Zhiyong Lou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009507

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https://doi.org/10.1371/journal.ppat.1009507

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