Updated Understanding of Cancer as a Metabolic and Telomere-Driven Disease, and Proposal for Complex Personalized Treatment, a Hypothesis

Updated Understanding of Cancer as a Metabolic and Telomere-Driven Disease, and Proposal for Complex Personalized Treatment, a Hypothesis

In this review, we propose a holistic approach to understanding cancer as a metabolic disease. Our search for relevant studies in medical databases concludes that cancer cells do not evolve directly from normal healthy cells. We hypothesize that aberrant DNA damage accumulates over time—avoiding the...

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Bibliographic Details
Main Authors: Cristian Muresanu, Siva G. Somasundaram, Sergey V. Vissarionov, Luis Fernando Torres Solis, Arturo Solís Herrera, Cecil E. Kirkland, Gjumrakch Aliev
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
DNA damage
cancer
DNA mutations
telomere
genetic
immune checkpoint therapy
Online Access:https://www.mdpi.com/1422-0067/21/18/6521

Internet

https://www.mdpi.com/1422-0067/21/18/6521

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