Histone Deacetylases: Molecular Mechanisms and Therapeutic Implications for Muscular Dystrophies

Histone Deacetylases: Molecular Mechanisms and Therapeutic Implications for Muscular Dystrophies

Histone deacetylases (HDACs) are enzymes that regulate the deacetylation of numerous histone and non-histone proteins, thereby affecting a wide range of cellular processes. Deregulation of HDAC expression or activity is often associated with several pathologies, suggesting potential for targeting th...

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Bibliographic Details
Main Authors: Martina Sandonà, Giorgia Cavioli, Alessandra Renzini, Alessia Cedola, Giuseppe Gigli, Dario Coletti, Timothy A. McKinsey, Viviana Moresi, Valentina Saccone
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
histone deacetylase
muscular dystrophies
Duchenne Muscular Dystrophy
clinical trials
Online Access:https://www.mdpi.com/1422-0067/24/5/4306

Internet

https://www.mdpi.com/1422-0067/24/5/4306

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