Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function

Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function

Acute kidney injury (AKI) induced by cisplatin (CP), a first-line anticancer drug for chemotherapy, is common. To date, there is an urgent need to find effective treatments to reduce the nephrotoxicity caused by CP. Meanwhile, the restoration of mitochondrial dysfunction shows potential to be used a...

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Bibliographic Details
Main Authors: Meng Zhou, Yanpeng Dai, Yong Ma, Yi Yan, Min Hua, Qi Gao, Xue Geng, Qian Zhou
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
liquiritigenin
NRF2
cisplatin
SIRT3
mitochondrial biogenesis
Online Access:https://www.mdpi.com/1420-3049/27/12/3823

Internet

https://www.mdpi.com/1420-3049/27/12/3823

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