The salivary metatranscriptome as an accurate diagnostic indicator of oral cancer

Abstract Despite advances in cancer treatment, the 5-year mortality rate for oral cancers (OC) is 40%, mainly due to the lack of early diagnostics. To advance early diagnostics for high-risk and average-risk populations, we developed and evaluated machine-learning (ML) classifiers using metatranscri...

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Bibliographic Details
Main Authors: Guruduth Banavar, Oyetunji Ogundijo, Ryan Toma, Sathyapriya Rajagopal, Yen Kai Lim, Kai Tang, Francine Camacho, Pedro J. Torres, Stephanie Gline, Matthew Parks, Liz Kenny, Ally Perlina, Hal Tily, Nevenka Dimitrova, Salomon Amar, Momchilo Vuyisich, Chamindie Punyadeera
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-021-00257-x