Arteannuin-B and (3-Chlorophenyl)-2-Spiroisoxazoline Derivative Exhibit Anti-Inflammatory Effects in LPS-Activated RAW 264.7 Macrophages and BALB/c Mice-Induced Proinflammatory Responses via Downregulation of NF-κB/P38 MAPK Signaling

Host inflammatory responses are key to protection against injury; however, persistent inflammation is detrimental and contributes to morbidity and mortality. Herein, we demonstrated the anti-inflammatory role of Arteannuin-B (<b>1</b>) and its new spirocyclic-2-isoxazoline derivative <...

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Main Authors: Gifty Sawhney, Javeed Ur Rasool, Diksha Saroch, Mumin Ozturk, Frank Brombacher, Bilal Ahmad, Asha Bhagat, Asif Ali, Suraj P. Parihar, Zabeer Ahmed
格式: 文件
语言:English
出版: MDPI AG 2022-11-01
丛编:Molecules
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在线阅读:https://www.mdpi.com/1420-3049/27/22/8068