Liraglutide Activates Glucagon-Like Peptide 1 Receptor to Attenuate Hyperglycemia through Endogenous Beta-Endorphin in Diabetic Rats

Liraglutide Activates Glucagon-Like Peptide 1 Receptor to Attenuate Hyperglycemia through Endogenous Beta-Endorphin in Diabetic Rats

Liraglutide, an acylated analog of glucagon-like peptide 1 (GLP-1), could improve glycemic control in diabetes. Moreover, endogenous opioid peptides play a role in blood sugar regulation. Since GLP-1 receptors are also expressed in extra-pancreatic tissues, this study investigates the effect of lira...

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Bibliographic Details
Main Authors: Kai-Chun Cheng, Ying-Xiao Li, Po-Chuen Shieh, Juei-Tang Cheng, Chia-Chen Hsu
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceuticals
Subjects:
liraglutide
GLP-1 receptor
beta-endorphin
adrenal gland
diabetic rats
Online Access:https://www.mdpi.com/1424-8247/13/11/407

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https://www.mdpi.com/1424-8247/13/11/407

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