Next-generation sequencing analysis of the human T-cell and B-cell receptor repertoire diversity before and after hepatitis B vaccination

Next-generation sequencing analysis of the human T-cell and B-cell receptor repertoire diversity before and after hepatitis B vaccination

The hepatitis B (HB) vaccine effectively prevents the incidence of hepatitis B virus (HBV) infection. However, vaccine failure occurs in 5–10% of the recipients. The precise mechanisms leading to responsiveness to the HB vaccine are poorly understood. High-throughput sequencing (HTS) may help clarif...

Full description

Bibliographic Details
Main Authors: Akio Miyasaka, Yuichi Yoshida, Ting Wang, Yasuhiro Takikawa
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
hepatitis b vaccine
t-cell receptor
b-cell receptor
repertoire
diversity
complementary determining region 3
Online Access:http://dx.doi.org/10.1080/21645515.2019.1600987

Internet

http://dx.doi.org/10.1080/21645515.2019.1600987

Similar Items