Amide Moieties Modulate the Antimicrobial Activities of Conjugated Oligoelectrolytes against Gram‐negative Bacteria

Amide Moieties Modulate the Antimicrobial Activities of Conjugated Oligoelectrolytes against Gram‐negative Bacteria

Abstract Cationic conjugated oligoelectrolytes (COEs) are a class of compounds that can be tailored to achieve relevant in vitro antimicrobial properties with relatively low cytotoxicity against mammalian cells. Three distyrylbenzene‐based COEs were designed containing amide functional groups on the...

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Bibliographic Details
Main Authors: Jakkarin Limwongyut, Dr. Alex S. Moreland, Dr. Chenyao Nie, Prof. Javier Read de Alaniz, Prof. Guillermo C. Bazan
Format: Article
Language:English
Published: Wiley-VCH 2022-02-01
Series:ChemistryOpen
Subjects:
antimicrobial agents
amides
conjugated oligoelectrolytes
membrane disruption
structure-activity relationships
Online Access:https://doi.org/10.1002/open.202100260

Internet

https://doi.org/10.1002/open.202100260

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