Tobacco smoke activates human papillomavirus 16 p97 promoter and cooperates with high-risk E6/E7 for oxidative DNA damage in lung cells.

Tobacco smoke activates human papillomavirus 16 p97 promoter and cooperates with high-risk E6/E7 for oxidative DNA damage in lung cells.

We have previously shown a functional interaction between human papillomavirus type 16 (HPV-16) E6 and E7 oncoproteins and cigarette smoke condensate (CSC) in lung cells suggesting cooperation during carcinogenesis. The molecular mechanisms of such interaction, however, remain to be elucidated. Here...

Full description

Bibliographic Details
Main Authors: Nelson Peña, Diego Carrillo, Juan P Muñoz, Jonás Chnaiderman, Ulises Urzúa, Oscar León, Maria L Tornesello, Alejandro H Corvalán, Ricardo Soto-Rifo, Francisco Aguayo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4382149?pdf=render

Internet

http://europepmc.org/articles/PMC4382149?pdf=render

Similar Items