The Protective Effect of Glibenclamide in a Model of Hemorrhagic Encephalopathy of Prematurity

The Protective Effect of Glibenclamide in a Model of Hemorrhagic Encephalopathy of Prematurity

We studied a model of hemorrhagic encephalopathy of prematurity (EP) that closely recapitulates findings in humans with hemorrhagic EP. This model involves tandem insults of 20 min intrauterine ischemia (IUI) plus an episode of elevated venous pressure induced by intraperitoneal glycerol on post-nat...

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Bibliographic Details
Main Authors: J. Marc Simard, Volodymyr Gerzanich, Turhan Coksaygan, Svetlana Ivanova, Gary Schwartzbauer, Melda Gurakar, Hina Ijaz, Cigdem Tosun, Michael T. Koltz, David B. Kurland
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Brain Sciences
Subjects:
encephalopathy of prematurity
germinal matrix hemorrhage
intraventricular hemorrhage
choroid plexus hemorrhage
sulfonylurea receptor 1
glibenclamide
Online Access:http://www.mdpi.com/2076-3425/3/1/215

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http://www.mdpi.com/2076-3425/3/1/215

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