Enrichment of Tc1 cells and T cell resistance to suppression are associated with dysglycemia in the visceral fat in human obesity

ObjectiveInsulin resistance, defined as tissue inflammation leading to type 2 diabetes, is a feature of obesity. The immune system has been implicated in its pathogenesis, but the role of adaptive immunity in humans remains uncertain. Here, we aim to determine whether specific phenotypic and functio...

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Bibliographic Details
Main Authors: Sara Cardellini, Carlo Socci, Massimiliano Bissolati, Fioralba Pindozzi, Anna Giovenzana, Alessandro Saibene, Emanuele Bosi, Manuela Battaglia, Alessandra Petrelli
Format: Article
Language:English
Published: BMJ Publishing Group 2020-04-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/8/1/e000772.full