Hormone therapy is associated with lower Alzheimer’s disease tau biomarkers in post-menopausal females -evidence from two independent cohorts

Abstract Background Females represent approximately 70% of the Alzheimer’s disease (AD) cases and the literature has proposed a connection between the decreased estrogen levels during menopause and an increased AD risk. Previous investigations have predominantly focused on assessing how hormone ther...

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Bibliographic Details
Main Authors: Yi-Ting Wang, Joseph Therriault, Cécile Tissot, Stijn Servaes, Nesrine Rahmouni, Arthur Cassa Macedo, Jaime Fernandez-Arias, Sulantha S. Mathotaarachchi, Jenna Stevenson, Firoza Z. Lussier, Andréa L. Benedet, Tharick A. Pascoal, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Serge Gauthier, Pedro Rosa-Neto
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Alzheimer’s Research & Therapy
Online Access:https://doi.org/10.1186/s13195-024-01509-5