TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification

TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification

Abstract Background Neoantigen-based personal vaccines and adoptive T cell immunotherapy have shown high efficacy as a cancer treatment in clinical trials. Algorithms for the accurate prediction of neoantigens have played a pivotal role in such studies. Some existing bioinformatics methods, such as...

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Bibliographic Details
Main Authors: Yunxia Tang, Yu Wang, Jiaqian Wang, Miao Li, Linmin Peng, Guochao Wei, Yixing Zhang, Jin Li, Zhibo Gao
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Bioinformatics
Subjects:
Neoantigen
Multiple factors
Recall rate
Positive rate
Top-ranked
Online Access:http://link.springer.com/article/10.1186/s12859-020-03869-9

Internet

http://link.springer.com/article/10.1186/s12859-020-03869-9

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