PTEN Tumor-Suppressor: The Dam of Stemness in Cancer

PTEN Tumor-Suppressor: The Dam of Stemness in Cancer

<i>PTEN</i> is one of the most frequently inactivated tumor suppressor genes in cancer. Loss or variation in <i>PTEN</i> gene/protein levels is commonly observed in a broad spectrum of human cancers, while germline <i>PTEN</i> mutations cause inherited syndromes t...

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Bibliographic Details
Main Authors: Francesca Luongo, Francesca Colonna, Federica Calapà, Sara Vitale, Micol E. Fiori, Ruggero De Maria
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cancers
Subjects:
cancer stem cells
PTEN
therapy resistance
targeted therapy
Online Access:https://www.mdpi.com/2072-6694/11/8/1076

Internet

https://www.mdpi.com/2072-6694/11/8/1076

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