Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA

The SOSS1 complex comprising SOSSA, SOSSB1, and SOSSC senses single-stranded DNA (ssDNA) and promotes repair of DNA double-strand breaks (DSBs). But how SOSS1 is assembled and recognizes ssDNA remains elusive. The crystal structure of the N-terminal half of SOSSA (SOSSAN) in complex with SOSSB1 and...

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Bibliografische gegevens
Hoofdauteurs: Wendan Ren, Hongxia Chen, Qiangzu Sun, Xuhua Tang, Siew Choo Lim, Jun Huang, Haiwei Song
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 2014-03-01
Reeks:Cell Reports
Online toegang:http://www.sciencedirect.com/science/article/pii/S221112471400120X