Rare Variants in Primary Immunodeficiency Genes and Their Functional Partners in Severe COVID-19

Rare Variants in Primary Immunodeficiency Genes and Their Functional Partners in Severe COVID-19

The development of severe COVID-19, which is a complex multisystem disease, is thought to be associated with many genes whose action is modulated by numerous environmental and genetic factors. In this study, we focused on the ideas of the omnigenic model of heritability of complex traits, which assu...

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Bibliographic Details
Main Authors: Maryam B. Khadzhieva, Dmitry S. Kolobkov, Darya A. Kashatnikova, Alesya S. Gracheva, Ivan V. Redkin, Artem N. Kuzovlev, Lyubov E. Salnikova
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomolecules
Subjects:
severe COVID-19
primary immunodeficiency (PID) genes
protein-protein interaction (PPI)
functional partners (FPs) of PID genes
omnigenic model
core and peripheral genes
Online Access:https://www.mdpi.com/2218-273X/13/9/1380

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https://www.mdpi.com/2218-273X/13/9/1380

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