Inflammation-related citrullination of matrisome proteins in human cancer

Inflammation-related citrullination of matrisome proteins in human cancer

IntroductionProtein arginine deiminases (PADs) are intracellular enzymes that may, especially in pathological conditions, also citrullinate extracellular substrates, including matrisome proteins such as structural proteins in extracellular matrix (ECM). PADs are abundantly expressed in human cancer...

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Bibliographic Details
Main Authors: Pekka Rappu, Ujjwal Suwal, Elina Siljamäki, Jyrki Heino
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
citrullination
inflammation
extracellular matrix
cancer
proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1035188/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1035188/full

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