Alveolar type II cells possess the capability of initiating lung tumor development.

Identifying cells of tumor origin is a fundamental question in tumor biology. Answers to this central question will not only advance our understanding of tumor initiation and progression but also have important therapeutic implications. In this study, we aimed to uncover the cells of origin of lung...

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Bibliographic Details
Main Authors: Chuwen Lin, Hai Song, Cecilia Huang, Erica Yao, Rhodora Gacayan, Shan-Mei Xu, Pao-Tien Chuang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3527621?pdf=render