Aqueous extract of the edible Gracilaria tenuistipitata inhibits hepatitis C viral replication via cyclooxygenase-2 suppression and reduces virus-induced inflammation.

Hepatitis C virus (HCV) is an important human pathogen leading to hepatocellular carcinoma. Using an in vitro cell-based HCV replicon and JFH-1 infection system, we demonstrated that an aqueous extract of the seaweed Gracilaria tenuistipitata (AEGT) concentration-dependently inhibited HCV replicatio...

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Bibliographic Details
Main Authors: Kuan-Jen Chen, Chin-Kai Tseng, Fang-Rong Chang, Jin-Iong Yang, Chi-Chen Yeh, Wei-Chun Chen, Shou-Fang Wu, Hsueh-Wei Chang, Jin-Ching Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585194?pdf=render