Attenuated levels of hippocampal connexin 43 and its phosphorylation correlate with antidepressant- and anxiolytic-like activities in mice

Attenuated levels of hippocampal connexin 43 and its phosphorylation correlate with antidepressant- and anxiolytic-like activities in mice

Clinical and preclinical studies have implicated glial anomalies in major depression. Conversely, evidence suggests that the activity of antidepressant drugs is based, at least in part, on their ability to stimulate density and/or activity of astrocytes, a major glial cell population. Despite this r...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Gaël eQuesseveur, Benjamin ePortal, Jean-Arnaud eBasile, Pascal eEzan, Alexia eMathou, Hélène eHalley, Corinne eLeloup, Xavier eFioramonti, Nicole eDéglon, Christian eGiaume, Claire eRampon, Bruno Pierre Guiard
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Frontiers Media S.A. 2015-12-01
Sarja:Frontiers in Cellular Neuroscience
Aiheet:
Anxiety
Astrocytes
Behavior
Connexin 43
Depression
Hippocampus
Linkit:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00490/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00490/full

Samankaltaisia teoksia