Astragaloside IV inhibits pathological functions of gastric cancer-associated fibroblasts through regulation of the HOXA6/ZBTB12 axis

Astragaloside IV inhibits pathological functions of gastric cancer-associated fibroblasts through regulation of the HOXA6/ZBTB12 axis

Cancer-associated fibroblasts (CAFs) play critical roles in the tumor microenvironment and exert tumor-promoting or tumor-retarding effects on cancer development. Astragaloside IV has been suggested to rescue the pathological impact of CAFs in gastric cancer. This study aimed to investigate the pote...

Full description

Bibliographic Details
Main Authors: Liu Haibo, Luo Shicheng, Sha Xiaofeng, Chen Zhiping, Yang Dongdong
Format: Article
Language:English
Published: Sciendo 2023-09-01
Series:Acta Pharmaceutica
Subjects:
astragaloside iv
cancer-associated fibroblasts
hoxa6
zbtb12
Online Access:https://doi.org/10.2478/acph-2023-0033

Internet

https://doi.org/10.2478/acph-2023-0033

Similar Items