Type I interferon score is associated with the severity and poor prognosis in anti-MDA5 antibody-positive dermatomyositis patients

Type I interferon score is associated with the severity and poor prognosis in anti-MDA5 antibody-positive dermatomyositis patients

ObjectivesTo investigate the clinical significance of the interferon (IFN) score, especially the IFN-I score, in patients with anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (anti-MDA5+ DM).MethodsWe enrolled 262 patients with different autoimmune diseases,...

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Bibliographic Details
Main Authors: Jinjing Qian, Rui Li, Zhiwei Chen, Zehui Cao, Liangjing Lu, Qiong Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
dermatomyositis
anti-MDA5 antibody
interstitial lung disease (ILD)
IFN signature
multiplex RT-qPCR assay
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151695/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151695/full

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