Enhancing gastric cancer conventional chemotherapy effects by triple angiokinase inhibitor nintedanib in preclinical models

Enhancing gastric cancer conventional chemotherapy effects by triple angiokinase inhibitor nintedanib in preclinical models

BackgroundGastric adenocarcinoma (GAC) is the fourth leading cause of cancer death worldwide. Systemic chemotherapy is a preferred treatment option for advanced and recurrent GAC, but response rates and survival prolongation remain limited. Tumor angiogenesis plays a critical role in GAC growth, inv...

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Bibliographic Details
Main Authors: Niranjan Awasthi, Margaret A. Schwarz, Quinn Kaurich, Changhua Zhang, Frank Hilberg, Roderich E. Schwarz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
chemotherapy
nintedanib
angiogenesis
combination therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1145999/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1145999/full

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