Transcriptional dissection of human limbal niche compartments by massive parallel sequencing.

Corneal epithelium is maintained throughout life by well-orchestrated proliferation of limbal epithelial stem cells (LESCs), followed by migration and maturation centripetally towards the ocular surface. Disturbance of LESCs can potentially lead to a blinding condition, which can be reversed by reco...

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Bibliographic Details
Main Authors: Chris Bath, Danson Muttuvelu, Jeppe Emmersen, Henrik Vorum, Jesper Hjortdal, Vladimir Zachar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3661480?pdf=render