Efficient Estimation of Mutation Rates during Individual Development by Minimization of Chi-Square.

Mutation primarily occurs when cells divide and it is highly desirable to have knowledge of the rate of mutations for each of the cell divisions during individual development. Recently, recessive lethal or nearly lethal mutations which were observed in a large mutation accumulation experiment using...

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Bibliographic Details
Main Authors: Shi-Meng Ai, Jian-Jun Gao, Shu-Qun Liu, Yun-Xin Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4534375?pdf=render