Foxh1/Nodal Defines Context-Specific Direct Maternal Wnt/β-Catenin Target Gene Regulation in Early Development

Summary: Although Wnt/β-catenin signaling is generally conserved and well understood, the regulatory mechanisms controlling context-specific direct Wnt target gene expression in development and disease are still unclear. The onset of zygotic gene transcription in early embryogenesis represents an id...

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Bibliographic Details
Main Authors: Boni A. Afouda, Yukio Nakamura, Sophie Shaw, Rebekah M. Charney, Kitt D. Paraiso, Ira L. Blitz, Ken W.Y. Cho, Stefan Hoppler
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220305010