Liquid-liquid phase separation of nucleocapsid proteins during SARS-CoV-2 and HIV-1 replication

Summary: The leap of retroviruses and coronaviruses from animal hosts to humans has led to two ongoing pandemics and tens of millions of deaths worldwide. Retrovirus and coronavirus nucleocapsid proteins have been studied extensively as potential drug targets due to their central roles in virus repl...

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Bibliographic Details
Main Authors: Bao-An Chau, Venessa Chen, Alan W. Cochrane, Leslie J. Parent, Andrew J. Mouland
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722018721