Evaluation of Anti-<i>Trypanosoma cruzi</i> Activity of Chemical Constituents from <i>Baccharis sphenophylla</i> Isolated Using High-Performance Countercurrent Chromatography

Evaluation of Anti-<i>Trypanosoma cruzi</i> Activity of Chemical Constituents from <i>Baccharis sphenophylla</i> Isolated Using High-Performance Countercurrent Chromatography

Endemic in 21 countries, Chagas disease, also known as American Trypanosomiasis, is a neglected tropical disease (NTD) caused by the protozoan parasite <i>Trypanosoma cruzi</i>. The available drugs for the treatment of this disease, benznidazole and nifurtimox, are outdated and display s...

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Bibliographic Details
Main Authors: Matheus L. Silva, Felipe S. Sales, Erica V. C. Levatti, Guilherme M. Antar, Andre G. Tempone, João Henrique G. Lago, Gerold Jerz
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Molecules
Subjects:
<i>Baccharis sphenophylla</i>
Asteraceae
diterpenes
flavonoids
<i>Trypanosoma cruzi</i>
high-performance countercurrent chromatography
Online Access:https://www.mdpi.com/1420-3049/29/1/212

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https://www.mdpi.com/1420-3049/29/1/212

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