Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis

Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis

Liver-resident natural killer cells develop locally and have multiple immunological roles in situ. Here the authors investigate the gut-liver axis and show the impact of the intestinal microbiota on the development of liver-resident natural killer cells.

Bibliographic Details
Main Authors: Panpan Tian, Wenwen Yang, Xiaowei Guo, Tixiao Wang, Siyu Tan, Renhui Sun, Rong Xiao, Yuzhen Wang, Deyan Jiao, Yachen Xu, Yanfei Wei, Zhuanchang Wu, Chunyang Li, Lifen Gao, Chunhong Ma, Xiaohong Liang
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37419-7

Internet

https://doi.org/10.1038/s41467-023-37419-7

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