Report of two pedigrees with heterozygous HTRA1 variants‐related cerebral small vessel disease and literature review

Report of two pedigrees with heterozygous HTRA1 variants‐related cerebral small vessel disease and literature review

Abstract Background Biallelic HTRA1 pathogenic variants are associated with autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). Recent studies have indicated that heterozygous HTRA1 variants are related to autosomal dominant hereditary cerebral smal...

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Bibliographic Details
Main Authors: Hui Zhou, Bin Jiao, Ziyu Ouyang, Qihui Wu, Lu Shen, Liangjuan Fang
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
Alzheimer's disease
CARASIL
cerebral small vessel disease
heterozygous variant
HTRA1
Online Access:https://doi.org/10.1002/mgg3.2032

Internet

https://doi.org/10.1002/mgg3.2032

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