Association between adeno‐associated virus genomic titers and intracellular plasmid levels

Abstract The recombinant adeno‐associated viral (rAAV) vector is one of the most effective viral vectors in gene therapy because of its low immunogenicity, high transduction efficiency, broad tissue specificity, and long‐term transgene expression ability. HEK293T cells are widely used to produce rAA...

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Bibliographic Details
Main Authors: Kyoko Masumi‐Koizumi, Yuzhe Yuan, Kiyoko Higashiyama, Keisuke Yusa, Kazuhisa Uchida
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Engineering Reports
Subjects:
Online Access:https://doi.org/10.1002/eng2.12704