Metformin Treatment Modulates Long Non-Coding RNA Isoforms Expression in Human Cells

Metformin Treatment Modulates Long Non-Coding RNA Isoforms Expression in Human Cells

Long noncoding RNAs (lncRNAs) undergo splicing and have multiple transcribed isoforms. Nevertheless, for lncRNAs, as well as for mRNA, measurements of expression are routinely performed only at the gene level. Metformin is the first-line oral therapy for type 2 diabetes mellitus and other metabolic...

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Bibliographic Details
Main Authors: Izabela Mamede C. A. da Conceição, Thomaz Luscher-Dias, Lúcio R. Queiroz, Ana Gabrielle B. de Melo, Carlos Renato Machado, Karina B. Gomes, Renan P. Souza, Marcelo R. Luizon, Glória R. Franco
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Non-Coding RNA
Subjects:
lncRNA
metformin
transcriptome
RNA isoforms
Online Access:https://www.mdpi.com/2311-553X/8/5/68

Internet

https://www.mdpi.com/2311-553X/8/5/68

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