Primary and Acquired Resistance to Immunotherapy in Lung Cancer: Unveiling the Mechanisms Underlying of Immune Checkpoint Blockade Therapy

Primary and Acquired Resistance to Immunotherapy in Lung Cancer: Unveiling the Mechanisms Underlying of Immune Checkpoint Blockade Therapy

After several decades without maintained responses or long-term survival of patients with lung cancer, novel therapies have emerged as a hopeful milestone in this research field. The appearance of immunotherapy, especially immune checkpoint inhibitors, has improved both the overall survival and qual...

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Bibliographic Details
Main Authors: Laura Boyero, Amparo Sánchez-Gastaldo, Miriam Alonso, José Francisco Noguera-Uclés, Sonia Molina-Pinelo, Reyes Bernabé-Caro
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
lung cancer
immunotherapy
resistance mechanisms
PD-1/PD-L1
immune checkpoint inhibitors
monoclonal antibodies
Online Access:https://www.mdpi.com/2072-6694/12/12/3729

Internet

https://www.mdpi.com/2072-6694/12/12/3729

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