Long-term engraftment of human natural T regulatory cells in NOD/SCID IL2rγc(null) mice by expression of human IL-2.

Regulatory T cells are essential to maintain immune homeostasis and prevent autoimmunity. Therapy with in vitro expanded human nT(Regs) is being tested to prevent graft versus host disease, which is a major cause for morbidity and mortality associated with hematopoietic stem cell transplantation. Th...

Full description

Bibliographic Details
Main Authors:	Sojan Abraham, Rajendra Pahwa, Chunting Ye, Jang-Gi Choi, Savita Pahwa, Shashidhar Jaggaiahgari, Ashwin Raut, Shuiping Chen, N Manjunath, Premlata Shankar
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3525660?pdf=render

Internet

http://europepmc.org/articles/PMC3525660?pdf=render

Long-term engraftment of human natural T regulatory cells in NOD/SCID IL2rγc(null) mice by expression of human IL-2.

Internet

Similar Items