MicroRNA-486-5p suppresses inflammatory response by targeting FOXO1 in MSU-treated macrophages

Gouty arthritis (GA) is mainly caused by the precipitation of monosodium urate (MSU) crystals in the joint. Recently, different regulatory roles of microRNAs (miRNAs) in arthritis have been widely verified. Nevertheless, the specific function of microRNA-486-5p (miR-486-5p) in GA is still unclear. G...

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Bibliographic Details
Main Authors: Jianguo Hu, Cheng Jin, Li Fang, Yao Lu, Yanying Wu, Xiangfeng Xu, Simei Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Autoimmunity
Subjects:
Online Access:http://dx.doi.org/10.1080/08916934.2022.2128780