Mitochondria-targeted antioxidant protects against irradiation-induced salivary gland hypofunction

Abstract A severe consequence of radiation therapy in patients with head and neck cancer is persistent salivary gland hypofunction which causes xerostomia and oral infections. We previously showed that irradiation (IR) of salivary glands in mice triggers initial transient increases in mitochondrial...

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Bibliographic Details
Main Authors: Xibao Liu, Krishna P. Subedi, Changyu Zheng, Indu Ambudkar
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86927-3