Mitochondria-targeted antioxidant protects against irradiation-induced salivary gland hypofunction
Abstract A severe consequence of radiation therapy in patients with head and neck cancer is persistent salivary gland hypofunction which causes xerostomia and oral infections. We previously showed that irradiation (IR) of salivary glands in mice triggers initial transient increases in mitochondrial...
Main Authors: | Xibao Liu, Krishna P. Subedi, Changyu Zheng, Indu Ambudkar |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-86927-3 |
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