Bone resorptive activity of osteoclast-like cells generated in vitro by PEG-induced macrophage fusion
Normal bone remodeling is maintained by a balance between osteoclast and osteoblast activity, whereas defects in osteoclast activity affecting such balance result in metabolic bone disease. Macrophage-macrophage fusion leading to multinucleated osteoclasts being formed is still not well understood....
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-01-01
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Series: | Biological Research |
Subjects: | |
Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000200009 |