Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we investigated whether spike proteins of SARS-CoV-2 induce LDs in human peripheral blood mononuclear cells (PBMCs) and in pulmonary microvascula...

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Bibliographic Details
Main Authors: Kokilavani Sivaraman, Paco Pino, Guillaume Raussin, Stephanie Anchisi, Charles Metayer, Nicolas Dagany, Julia Held, Sabine Wrenger, Tobias Welte, Maria J. Wurm, Florian M. Wurm, Beata Olejnicka, Sabina Janciauskiene
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Microorganisms
Subjects:
recombinant spike protein
human PBMCs
lung microvascular endothelial cells
cytokines
chemokines
lipid droplets
Online Access:https://www.mdpi.com/2076-2607/11/11/2683

Internet

https://www.mdpi.com/2076-2607/11/11/2683

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