Unilateral Perforant Path Transection Does Not Alter Lateral Entorhinal Cortical or Hippocampal CA3 Arc Expression

It is well established that degradation of perforant path fibers is associated with age-related cognitive dysfunction and CA3 hyperactivity. Whether this fiber loss triggers a cascade of other functional changes within the hippocampus circuit has not been causatively established, however. Thus, the...

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Bibliographic Details
Main Authors: Tara L. Cooper, John J. Thompson, Sean M. Turner, Cory Watson, Katelyn N. Lubke, Carly N. Logan, Andrew P. Maurer, Sara N. Burke
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnsys.2022.920713/full