Physical Interactions and Expression Quantitative Traits Loci Identify Regulatory Connections for Obesity and Type 2 Diabetes Associated SNPs

The mechanisms that underlie the association between obesity and type 2 diabetes are not fully understood. Here, we investigated the role of the 3D genome organization in the pathogeneses of obesity and type-2 diabetes. We interpreted the combined and differential impacts of 196 diabetes and 390 obe...

Full description

Bibliographic Details
Main Authors: Tayaza Fadason, Cameron Ekblad, John R. Ingram, William S. Schierding, Justin M. O'Sullivan
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00150/full