Actin fenestrae amplify the membrane response to hypertonic stress in osmosensory neurons

Summary: Osmosensory neurons detect hypertonic stress when ΔN-TRPV1 channels are activated through a push force delivered by microtubules during cell shrinking, and this process requires an essential yet unknown contribution from actin filaments. Here, we show that the actin cortex of these neurons...

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Bibliographic Details
Main Authors: Anzala Murtaz, Charles W. Bourque
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225003025