A comparison of Methods for Data-Driven Cancer Outlier Discovery, and An Application Scheme to Semisupervised Predictive Biomarker Discovery

A core component in translational cancer research is biomarker discovery using gene expression profiling for clinical tumors. This is often based on cell line experiments; one population is sampled for inference in another. We disclose a semisupervised workflow focusing on binary (switch-like, bimod...

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Bibliographic Details
Main Authors: Seppo Karrila, Julian Hock Ean Lee, Greg Tucker-Kellogg
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S6868